Knowledgeable
Use case · AMNOG dossier

AMNOG dossier

Module 4, ready for G-BA, in nine days.

Knowledgeable maps your competing treatment, drafts the clinical benefit narrative against G-BA's expectations and traces every claim back to the trial publication, label or SmPC. Your senior reviewer opens a document that is already at QC, not at first draft.

9d
from first draft to QC
100%
claims source-linked
−70%
rework after senior review
Knowledgeable Live

Watch it run on your work.

Director, Market Access · German biotech
A scripted demo · click Continue below (or press Space) to send the brief and walk through the work step by step.
Grounded in 12 sources · audit-logged
Director, Market Access · German biotechdraft
Click send to brief Knowledgeable…
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Background & context

Where this fits in your workflow.

Knowledgeable maps your competing treatment, drafts the clinical benefit narrative against G-BA's expectations and traces every claim back to the trial publication, label or SmPC. Your senior reviewer opens a document that is already at QC, not at first draft.

Most teams running AMNOG today juggle a stack of search tools, PDF readers and consultancy slides, then spend the back half of the project reconciling claims to sources. Knowledgeable collapses that into one defensible workflow: module 4, ready for g-ba, in nine days.

The work runs against your literature, trial registries, HTA precedent, label and SmPC, with every sentence pinpoint-cited so your senior reviewer opens a document that's already at QC.

Evidence sources
Published literatureTrial registriesHTA precedentLabel / SmPCConference abstractsReal-world data
How it runs
  1. 1Scope & competing treatment locked
  2. 2Evidence pulled & graded
  3. 3Draft built with citations
  4. 4QC pass against framework
What changes

The work that finally lands the way you scoped it.

Reviewer-shaped, not template-shaped

Sections, competing treatments and appendices land where the G-BA assessor actually looks. No reformat sprint the night before submission.

6 weeks → 9 days

Every claim sourced

Pinpoint citation to publication, SmPC or label on every sentence. Your QA lead audits in an afternoon, not a fortnight.

100% source-linked

Competing treatment pre-mapped

G-BA competing treatment logic pre-applied across the indication tree so the dossier does not get bounced on a definition.

Competing treatment audit in one click

Pre-built rebuttals

Anticipated objections and a rebuttal pack grounded in published precedent, ready before the IQWiG report lands.

Rebuttal pack · same week

Bring your next AMNOG into one system.

Pressure-test your next AMNOG
Responsible AI · Enterprise security

Pre-answered for G-BA, IQWiG, medical and legal review, and InfoSec.

EU AI Act mapping, DPA, sub-processor list, SSO with 2FA, audit log, EU residency. Packaged the way your DPO and InfoSec want to see them.

EU AI Act alignedSSO + MFAAES-256 + TLS 1.2+EU / UK data residencyFull audit trail
Pre-answered for information security, medical and legal review, and procurement.