Knowledgeable
Use case · Pipeline prioritisation

Pipeline prioritisation

Portfolio calls grounded in evidence, not in vibes.

Knowledgeable scores every asset and indication against competitor pipeline, HTA precedent, addressable population and pricing corridor, so the portfolio review committee is debating the trade-offs, not the data.

Whole portfolio
assets scored
Source-linked
scoring
Continuous
refresh cadence
Knowledgeable Live

Watch it run on your work.

Chief Strategy Officer
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Grounded in 12 sources · audit-logged
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Background & context

Where this fits in your workflow.

Knowledgeable scores every asset and indication against competitor pipeline, HTA precedent, addressable population and pricing corridor, so the portfolio review committee is debating the trade-offs, not the data.

Most teams running Portfolio today juggle a stack of search tools, PDF readers and consultancy slides, then spend the back half of the project reconciling claims to sources. Knowledgeable collapses that into one defensible workflow: portfolio calls grounded in evidence, not in vibes.

The work runs against your literature, trial registries, HTA precedent, label and SmPC, with every sentence pinpoint-cited so your senior reviewer opens a document that's already at QC.

Evidence sources
Published literatureTrial registriesHTA precedentLabel / SmPCConference abstractsReal-world data
How it runs
  1. 1Scope & competing treatment locked
  2. 2Evidence pulled & graded
  3. 3Draft built with citations
  4. 4QC pass against framework
What changes

The work that finally lands the way you scoped it.

Asset and indication scoring

Every asset scored across every credible indication, not just the favourite ones.

Full matrix

Competitor-aware

Pipeline density, likely first-to-market, label race. Built into the score.

Pipeline-grounded

Access-aware

HTA precedent and pricing corridor in the score, so the prioritisation reflects what you can actually monetise.

Access-grounded

Defensible at the board

Every input sourced, every assumption logged. The portfolio review committee debates the call, not the data.

Board-defensible

Make the portfolio call you can defend.

Audit your portfolio
Responsible AI · Enterprise security

Audit-trailed at the asset level.

Sources, assumptions and scoring logic captured. Reproducible at every review.

EU AI Act alignedSSO + MFAAES-256 + TLS 1.2+EU / UK data residencyFull audit trail
Pre-answered for information security, medical and legal review, and procurement.