Knowledgeable
Use case · Targeted literature review

Targeted literature review

Targeted literature reviews focused, structured, in 1–2 days.

A tight PICO, a transparent search, structured extraction and a light risk-of-bias summary. Built for the questions that do not justify a six-month systematic literature review but deserve more rigour than a quick scoping pass. Use for payer questions, competing treatment deep-dives, advisory board preparation and internal evidence framing.

1–2 days
turnaround
Single reviewer + AI
screening
Not a PRISMA SLR
boundary
Knowledgeable Live

Watch it run on your work.

HEOR · evidence lead
A scripted demo · click Continue below (or press Space) to send the brief and walk through the work step by step.
Grounded in 9 sources · audit-logged
HEOR · evidence leaddraft
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Background & context

Where this fits in your workflow.

A tight PICO, a transparent search, structured extraction and a light risk-of-bias summary. Built for the questions that do not justify a six-month systematic literature review but deserve more rigour than a quick scoping pass. Use for payer questions, competing treatment deep-dives, advisory board preparation and internal evidence framing.

Most teams running TLR today juggle a stack of search tools, PDF readers and consultancy slides, then spend the back half of the project reconciling claims to sources. Knowledgeable collapses that into one defensible workflow: targeted literature reviews focused, structured, in 1–2 days.

The work runs against your literature, trial registries, HTA precedent, label and SmPC, with every sentence pinpoint-cited so your senior reviewer opens a document that's already at QC.

Evidence sources
Published literatureTrial registriesHTA precedentLabel / SmPCConference abstractsReal-world data
How it runs
  1. 1Scope & competing treatment locked
  2. 2Evidence pulled & graded
  3. 3Draft built with citations
  4. 4QC pass against framework
What changes

The work that finally lands the way you scoped it.

Focused PICO, locked early

Tight question scoping that keeps the review answerable in days, not quarters.

Day-1 PICO

Transparent, reproducible search

Search strategy logged and exportable. Not exhaustive like a full systematic review, but defensible and re-runnable.

Audit trail

Structured extraction

Population, intervention, competing treatment and outcomes captured into one reviewer-ready table.

Reusable grid

Honest boundary

Light risk-of-bias summary and an explicit statement of what this targeted review can, and cannot, support downstream.

Boundary stated

The right rigour for the question, not a method mismatch.

Scope a TLR
Responsible AI · Enterprise security

Right-sized rigour.

Focused, structured, audit-trailed. Built for the questions where a full systematic review is not justified but a quick scoping pass is not enough.

EU AI Act alignedSSO + MFAAES-256 + TLS 1.2+EU / UK data residencyFull audit trail
Pre-answered for information security, medical and legal review, and procurement.